Percocet (Oxycodone / Paracetamol) : Drug Information

What is Percocet?

Percocet is the trade name given to the combination of drugs named oxycodone and acetaminophen. Oxycodone is a pain medication. Acetaminophen in Percocet is a less potent pain reliever that increases the effectiveness of oxycodone. Percocet is prescribed by the doctors to treat pain ranging from moderate to severe. Even at prescribed doses, the risk of abuse, misuse, and addiction to this medication is high. Therefore, doctors only recommend Percocet when other medicines do not give the desired result. You can only avail of Percocet under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program initiated by the food and drug administration (FDA). You must be aware that buying or selling Percocet without proper prescription is an offense under the law.

What to know before taking Percocet?

You should not start with this medication if you are allergic to any of the components of Percocet or if you have or ever had the following health issues:

  • Asthma or any other breathing issue
  • Blockage in stomach or intestine

To ensure that this medication is safe for you, you must tell your doctor if you have or ever had the following:

  • Breathing problem
  • Sleep apnea
  • Liver infections
  • Drugs or alcohol addiction
  • Kidney disease
  • Thyroid
  • Head injuries or seizures
  • Gallbladder infection
  • Problem in pancreas

Nursing mothers should avoid taking this medication.

Expecting women should not use Percocet as it may harm an unborn baby.

How to take Percocet?

You should take Percocet exactly as prescribed by the doctor. You should follow all the directions related to prescriptions carefully. Never take Percocet in an extra amount or for a more extended period, as an overdose of this medication can be fatal. If you need any surgery or medical examination, you should tell your doctor about this medication.

Don’t stop using Percocet without your doctor’s advice; otherwise, you may experience withdrawal symptoms.  Never share your medicine with anyone, especially those who have a record of misuse or addiction to drugs. After completion of treatment, you should dispose of all the medicines properly.

Percocet dosage

The dosage of any medication is entirely dependent on the following factors.

  • Age of the patient
  • Symptoms
  • The seriousness of the conditions
  • Any other medication that the patient is using.

Dosage for pain ( moderate to severe)

Oral dosages in the form of capsules

For adults: 1 capsule after every six hours. The doctor may change your dose if they think fit.

For children: The doctors must suggest the dosage.

Oral dosages in the form of extended-release tablets

For adults: 2 tablets every 12 hours. The doctor may change your dose if they think fit.

For children: The doctors should not recommend Percocet extended-release tablets for the children.

Oral dosages in the form of solution

For adults: 5 ml or one teaspoon after every six hours. The doctor may further increase or decrease the dosages.

For children: The doctors must suggest the dosage.

Oral dosages in the form of tablets

For adults: 1 or 2 tablets every six hours. The doctor may change your dose if they think fit.

For children: The doctors must suggest the dosage

If you experience anything unbearable to you, consult your doctor as soon as possible.


If you ever experience the symptoms of an overdose of per Percocet, you should consult your doctor and ask for medical help immediately. You should not ignore these overdose symptoms as they can be very dangerous. You can avail of medical assistance by calling on 1-800-222-1222.

The following are some overdose symptoms that you should take care of.

  • Loss of appetite
  • Nausea
  • Vomiting
  • Stomach pain
  • Confusion
  • Weakness
  • Yellowness in eyes and on skin
  • Unusual urine
  • Slow breathing
  • Extreme drowsiness and dizziness.
  • Coma
  • Death

What to avoid while using Percocet?

You should avoid driving and using heavy machines till the time you feel affected by this medicine. Using this medication may cause you to feel extreme dizziness and drowsiness; therefore, you should try not to involve in an activity that requires a lot of attention. You should avoid alcohol because the interaction between these two can be dangerous. It will be best if you prevent medication errors.

Percocet side effects

If you use this kind of medication, you may experience some common side effects. It is ok to have these mild symptoms, but if you feel these symptoms are bothering too much, you should consult the doctor. Some of the common side effects of using Percocet are as follows:

  • Dizziness or drowsiness
  • Tiredness
  • Constipation
  • Stomach ache
  • Vomiting
  • Blurred vision
  • Mood swings
  • Itching
  • Red eyes

The list of symptoms mentioned above is inclusive. However, one can also experience some other severe symptoms such as

  • Noisy breathing, sighing, shallow breathing, breathing that stops during sleep.
  • Cold, clammy skin
  • Weakness, tiredness, fever, unusual bruising or bleeding
  • Seizure (convulsions)
  • Signs of liver problems including nausea, upper stomach pain, fatigue, loss of appetite, dark urine, clay-colored stools, jaundice
  • Nausea
  • Vomiting
  • Loss of appetite
  • Dizziness
  • Worsening tiredness, or weakness
  • Problems with urination
  • Confusion, unusual thoughts or behavior
  • A light-headed feeling
  • Slow heartbeat or week pulse

If you feel any other symptoms that bother you too much, you should consult your doctor immediately.

What drugs can interact with Percocet?

It would be best if you tell your doctor everything about your medical history. Before starting taking Percocet, you must say to the doctor about the medication you are currently taking. It is important because some medicines can interact with Percocet and result in some dangerous situations. Tell your doctor if you are taking:

  • Antibiotic medicines
  • Antifungal medications
  • Heart or blood pressure medicines
  • Seizure medication
  • Medicines to treat HIV
  • Medicines to treat hepatitis C
  • Cold or allergy medicines
  • Asthma or COPD medications
  • Medicines for motion sickness
  • Other Narcotic medications such as opioids, pain killer, or prescription cough medicines
  • Any sedative medication such as diazepam, xanax, etc
  • Sleeping pills
  • Medicines that affect the serotonin level in the body
  • Vitamin supplements
  • Herbal products
  • Medicines to treat mental illness
  • Anti-anxiety medication
  • Antidepressant

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